Ulcerative colitis is an inflammatory bowel disease (IBD) that causes long-term inflammation and ulcers in the digestive tract. Ulcerative colitis affects the innermost lining of the large intestine (colon) and rectum. Symptoms usually appear gradually over time, rather than suddenly.
Ulcerative colitis can be debilitating and sometimes life-threatening. Although there is no cure, treatment can significantly reduce the signs and symptoms of the disease and even achieve long-term remission.
The exact cause of ulcerative colitis remains unknown. Previously, diet and stress were suspected, but doctors now know that these factors can exacerbate but not cause ulcerative colitis.
One possible cause is a malfunction of the immune system. When your immune system tries to fight off an invading virus or bacteria, abnormal immune responses cause it to attack cells in the digestive tract as well.
Genetics also appears to play a role, making ulcerative colitis more common in people with family members who have the condition. However, most people with ulcerative colitis do not have a family history of the disease.
Types
Doctors often classify ulcerative colitis according to its location. Types of ulcerative colitis include:
1. Ulcerative proctitis: The inflammation is limited to the area closest to the anus (rectum), and rectal bleeding may be the only sign of the disease. This type of ulcerative colitis tends to be milder.
2. Sigmoidoproctitis: The inflammation involves the sigmoid colon and rectum (the lower end of the colon). Signs and symptoms include bloody diarrhea, abdominal pain and cramps, and an inability to have a bowel movement despite the urge to do so (tenesmus).
3. Left-sided colitis: The inflammation extends from the rectum to the sigmoid colon and descending colon. Signs and symptoms include bloody diarrhea, left-sided abdominal pain and cramps, and unintentional weight loss.
4. Pancolitis: Pancolitis often affects the entire colon and causes bouts of bloody diarrhea, which can be severe, abdominal pain and cramps, fatigue, and significant weight loss.
5. Severe acute ulcerative colitis: This rare type of colitis affects the entire colon and causes severe pain, severe diarrhea, bleeding, fever, and an inability to eat.
Treatment for ulcerative colitis involves either medication or surgery.
Several classes of medications may be effective in treating ulcerative colitis. The type of medication you take will depend on the severity and location of your disease. Medications that work for some people may not work for others, so it may take time to find a medication that works for you.
Treatment
4.1 Medication
4.1.1 Nicotine
4.1.2 Iron supplements
4.2 Surgical treatment
4.3 Leukopenia
4.4 Alternative medicine
Surgery often eliminates ulcerative colitis. However, this usually involves removing the entire colon and rectum (proctocolectomy).
In most cases, this involves performing an ileal pouch-anal anastomosis procedure. This procedure eliminates the need to wear a bag to collect stool. The surgeon creates a pouch from the end of the small intestine. This pouch is then connected directly to the anus, allowing you to pass stool relatively naturally.
In some cases, a pouch is not possible. Instead, surgeons create a permanent opening in the abdomen (ileal stoma) through which stool is passed and collected in an attached bag.
Blood and urine tests
EKG and X-rays for those over 40
Hair removal at the procedure site
Shower and thorough cleaning of the procedure site